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The key to Thursday night’s game will be whether Indianapolis can generate enough offense against a Denver defense that came alive last week in a shutout win over the Jets. Colts quarterback Jacoby Brissett has three rushing touchdown in his last five home games. Running back Frank Gore is coming off a season-high 130 rushing yards in last week’s loss to the Bills. He needs just 59 scrimmage yards against the Broncos to become the second player in NFL history with 12-plus consecutive seasons with 1,000-plus scrimmage yards (Emmitt Smith, 13). 

BRONCOS VS. COLTS PICKS:Against the spread | Straight up

Here is all the info you need to watch Broncos vs. Colts on “Thursday Night Football.”

Broncos vs. Colts: Live stream, TV channel, network

Broncos vs. Colts: Live stream | Game Center

Kickoff time: 8:25 p.m. ET

TV networks: NBC, NFL Network

Radio: Sirius/XM channel 88 (Westwood One), 83 (Colts call), 81 (Broncos call)

Thursday night’s game in Indianapolis will air nationally on NBC and NFL Network. It’s the last of five Thursday night games that were scheduled to be televised on NBC throughout the season (not including the NFL season-opener) as part of the NFL’s “Thursday Night Football” expansion package for 2016 and ‘17. NBC also televised the Thanksgiving night game between the Giants and Redskins on Thursday, Nov. 23. CBS carried five Thursday night games earlier this year. In addition to CBS and NBC, NFL Network broadcasts every Thursday night game of the season.

“Thursday Night Football” is available in Spanish via SAP (Secondary Audio Program) with René Giraldo and Edgar López calling the action.

NFL PLAYOFF PICTURE:Current seeding | Clinching scenarios

Broncos vs. Colts: Picks, predictions, odds, point spread

Per Bovada, the Broncos are three-point road favorites against the Colts. The over/under points total was set at 40 1/2.

SN’s Vinnie Iyer in his Week 15 NFL picks against the spread picked the Broncos to beat the Colts in a close game, 20-16.

SN’s David Steele in his Week 15 NFL picks straight up picked the Colts to upset the Broncos, 23-13.